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CS-W001157 4
Total: USD 88.00

4-Bromo-2-fluoro-N,N-dimethylbenzamide

  • CAS No. 749927-80-8

  • Cat. No. CS-0186955
  • Molecule weight246.08
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2-fluoro-N,N-dimethylbenzamide|CS-0186955

Structure of 749927-80-8

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General Information

  • CAS No. 749927-80-8
  • Cat. No. CS-0186955
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉BrFNO
  • Molecular Weight 246.08
  • Synonym(s) 4-Bromo-N,N-dimethyl-2-fluorobenzamide
  • SMILES CN(C)C(=O)C1=C(C=C(C=C1)Br)F

Synthesis

  • Route1
    • null|null
      124-40-3
    • ~53%
    • In-stock
      4-Bromo-2-fluoro-N,N-dimethylbenzamide|CS-0186955
      749927-80-8

    References

    • ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2006/64251 A1, 2006 ; Location in patent: Page/Page column 62-63 ; WO 2006/064251 A1
  • Route2
    • null|null
      506-59-2
    • In-stock
      2-Fluoro-4-bromobenzoic acid|CS-M3187
      112704-79-7
    • ~96%
    • In-stock
      4-Bromo-2-fluoro-N,N-dimethylbenzamide|CS-0186955
      749927-80-8

    References

    • Zhu, Jason; Razler, Thomas M.; Xu, Zhongmin; Conlon, David A.; Sortore, Eric W.; Fritz, Alan W.; Demerzhan, Roman; Sweeney, Jason T. Organic Process Research and Development, 2011 , vol. 15, # 2 p. 438 - 442
  • Route3
    • null|null
      124-40-3
    • null|null
      151982-51-3
    • ~%
    • In-stock
      4-Bromo-2-fluoro-N,N-dimethylbenzamide|CS-0186955
      749927-80-8

    References

    • CROWN BIOSCIENCE INC. (TAICANG); ZHONG, Boyu; SHIH, Chuan; YUAN, Hongbin; ZHOU, Feng Patent: WO2014/32498 A1, 2014 ; Location in patent: Page/Page column 10 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.31
  • LogP   2.29
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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