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CS-W001157 4
Total: USD 88.00

DMAT

  • CAS No. 749234-11-5

  • Cat. No. CS-1289
  • Purity≥98%
  • MDL No.MFCD08705322

*For research and further manufacturing use only, not for direct human use.

DMAT|CS-1289

Structure of 749234-11-5

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General Information

  • CAS No. 749234-11-5
  • Cat. No. CS-1289
  • Purity ≥98%
  • MDL No. MFCD08705322
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇Br₄N₃
  • Molecular Weight 476.79
  • Synonym(s) CK2 Inhibitor; Casein kinase II Inhibitor
  • SMILES CN(C)C1=NC2=C(Br)C(Br)=C(Br)C(Br)=C2N1

Application

DMAT (CAS 749234-11-5) inhibits casein kinase 2 to disrupt parasite multiplication in [3H]-hypoxanthine incorporation assays, revealing critical metabolic vulnerabilities. It alters intracellular signaling in prostate cancer cells. This inhibition reduces cdc25C phosphatase levels, disrupting cell cycle progression and offering insights into targeted anticancer mechanisms.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   31.92
  • LogP   4.6789
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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