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CS-W001157 4
Total: USD 88.00

(2R,4R)-Ethyl 4-methylpiperidine-2-carboxylate Argatroban Impurity

  • CAS No. 74892-82-3

  • Cat. No. CS-0213872
  • Purity≥97%
  • MDL No.MFCD03093749

*For research and further manufacturing use only, not for direct human use.

(2R,4R)-Ethyl 4-methylpiperidine-2-carboxylate Argatroban Impurity|CS-0213872

Structure of 74892-82-3

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General Information

  • CAS No. 74892-82-3
  • Cat. No. CS-0213872
  • Purity ≥97%
  • MDL No. MFCD03093749
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₇NO₂
  • Molecular Weight 171.24
  • Synonym(s) Ethyl(2R,4R)-4-methyl-2-piperidinecarboxylate
  • SMILES O=C([C@@H]1NCC[C@@H](C)C1)OCC

Synthesis

  • Route1
    • null|null
      198641-56-4
    • ~45%
    • (2R,4R)-Ethyl 4-methylpiperidine-2-carboxylate Argatroban Impurity|CS-0213872
      74892-82-3

    References

    • Ferraboschi, Patrizia; Mieri, Maria De; Grisenti, Paride; Lotz, Matthias; Nettekoven, Ulrike Tetrahedron Asymmetry, 2011 , vol. 22, # 16-17 p. 1626 - 1631
  • Route2
    • null|null
      131278-84-7
    • ~90%
    • (2R,4R)-Ethyl 4-methylpiperidine-2-carboxylate Argatroban Impurity|CS-0213872
      74892-82-3

    References

    • LUNDBECK PHARMACEUTICALS ITALY S.P.A.; Stivanello, Mariano; Huber, Florian Anton Martin; Ricci, Antonio Patent: US2014/88310 A1, 2014 ; Location in patent: Paragraph 0090 ;
  • Route3
    • null|null
      134984-62-6
    • ~%
    • (2R,4R)-Ethyl 4-methylpiperidine-2-carboxylate Argatroban Impurity|CS-0213872
      74892-82-3

    References

    • Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 5 p. 1337 - 1340

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   0.9376
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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