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CS-W001157 4
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Phenyl n-(5-methyl-1,2-oxazol-3-yl)carbamate

  • CAS No. 74889-21-7

  • Cat. No. CS-0243549
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Phenyl n-(5-methyl-1,2-oxazol-3-yl)carbamate|CS-0243549

Structure of 74889-21-7

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General Information

  • CAS No. 74889-21-7
  • Cat. No. CS-0243549
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₀N₂O₃
  • Molecular Weight 218.21
  • Synonym(s) Phenyl 5-methylisoxazol-3-ylcarbamate
  • SMILES O=C(OC=1C=CC=CC1)NC2=NOC(=C2)C

Synthesis

  • Route1
    • 5-Methylisoxazol-3-amine Sulfamethoxazole  Impurity|CS-0229023
      1072-67-9
    • null|null
      1885-14-9
    • ~74%
    • Phenyl n-(5-methyl-1,2-oxazol-3-yl)carbamate|CS-0243549
      74889-21-7

    References

    • AMGEN INC. Patent: WO2009/58267 A2, 2009 ; Location in patent: Page/Page column 36; 38-39 ;
  • Route2

    References

    • De Lucca, George V.; Ui, Tae Kim; Vargo, Brian J.; Duncia, John V.; Santella III, Joseph B.; Gardner, Daniel S.; Zheng, Changsheng; Liauw, Ann; Wang, Zhang; Emmett, George; Wacker, Dean A.; Welch, Patricia K.; Covington, Maryanne; Stowell, Nicole C.; Wadman, Eric A.; Das, Anuk M.; Davies, Paul; Yeleswaram, Swamy; Graden, Danielle M.; Solomon, Kimberly A.; Newton, Robert C.; Trainor, George L.; Decicco, Carl P.; Ko, Soo S. Journal of Medicinal Chemistry, 2005 , vol. 48, # 6 p. 2194 - 2211

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   64.36
  • LogP   2.59392
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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