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CS-W001157 4
Total: USD 88.00

tert-Butyl 6-oxo-1,4-oxazepane-4-carboxylate

  • CAS No. 748805-97-2

  • Cat. No. CS-0037504
  • Purity≥95%
  • MDL No.MFCD11976154
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 6-oxo-1,4-oxazepane-4-carboxylate|CS-0037504

Structure of 748805-97-2

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Description

tert-Butyl 6-oxo-1,4-oxazepane-4-carboxylate is a bench-stable, moisture-tolerant heterocyclic building block featuring a ketone-functionalized oxazepane core. This scaffold integrates readily into medicinal chemistry campaigns requiring flexible nitrogen-containing ring systems with tunable reactivity at the C6 position.

Application

tert-Butyl 6-oxo-1,4-oxazepane-4-carboxylate serves as a versatile heterocyclic building block for the synthesis of oxazepane-containing scaffolds prevalent in medicinal chemistry. The ketone at C6 enables selective reductive amination and nucleophilic addition reactions, while the tert-butyl ester provides bench stability and facile deprotection under mild acidic conditions. Its functional group tolerance supports integration into multi-step synthetic sequences, facilitating access to complex nitrogen-containing ring systems relevant to drug discovery.

General Information

  • CAS No. 748805-97-2
  • Cat. No. CS-0037504
  • Purity ≥95%
  • MDL No. MFCD11976154
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₇NO₄
  • Molecular Weight 215.25
  • Synonym(s) None
  • SMILES O=C(N(C1)CCOCC1=O)OC(C)(C)C

Computational Chemistry Data

  • TPSA   55.84
  • LogP   0.8228
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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