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Structure of 7471-05-8
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This imidazolylpyridine scaffold integrates a labile dihydroimidazole ring with a pyridine moiety, enabling selective coordination in transition metal catalysis. The nitrogen-rich framework supports reversible binding and exhibits enhanced solubility in polar solvents, facilitating use in ligand design and synthetic transformations under standard conditions.
2-(4,5-Dihydro-1H-imidazol-2-yl)pyridine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient construction of bioactive scaffolds. Its imidazoline-pyridine fusion offers enhanced solubility and metabolic stability compared to fully aromatic analogs. The compound functions as a robust ligand in transition metal catalysis and participates reliably in C–H functionalization and cross-coupling reactions. Bench-stable and readily purified by standard chromatography, it supports scalable synthesis workflows and demonstrates broad compatibility with diverse reaction conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: