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CS-W001157 4
Total: USD 88.00

1-(Aminomethyl)cyclopropanol

  • CAS No. 74592-33-9

  • Cat. No. CS-W005471
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-(Aminomethyl)cyclopropanol|CS-W005471

Structure of 74592-33-9

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General Information

  • CAS No. 74592-33-9
  • Cat. No. CS-W005471
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉NO
  • Molecular Weight 87.12
  • Synonym(s) 1-(AMinoMethyl)cyclopropanol HCl
  • SMILES OC1(CN)CC1

Description

1-(Aminomethyl)cyclopropanol features a strained cyclopropane ring fused to a primary amine and hydroxyl group, enabling its use in bioactive molecule synthesis. The functionalized scaffold integrates readily into peptidomimetics and pharmaceutical intermediates, offering enhanced conformational rigidity and solubility under standard conditions.

Application

1-(Aminomethyl)cyclopropanol serves as a versatile building block in medicinal chemistry, enabling direct access to constrained β-amino alcohol scaffolds. Its cyclopropyl framework imparts enhanced metabolic stability and conformational rigidity, while the pendant primary amine and hydroxyl groups offer orthogonal reactivity for diverse functionalization. The compound exhibits excellent bench stability and facilitates efficient incorporation into peptidomimetics and heterocyclic cores via standard coupling and cyclization protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   -0.53
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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