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CS-W001157 4
Total: USD 88.00

Calix(4)arene

  • CAS No. 74568-07-3

  • Cat. No. CS-0197405
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Calix(4)arene|CS-0197405

Structure of 74568-07-3

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General Information

  • CAS No. 74568-07-3
  • Cat. No. CS-0197405
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₈H₂₄O₄
  • Molecular Weight 424.49
  • Synonym(s) pentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-25,26,27,28-tetrol
  • SMILES OC1=C(CC2=CC=CC(C3)=C2O)C=CC=C1CC4=CC=CC(CC5=CC=CC3=C5O)=C4O

Description

Calix(4)arene delivers a rigid, cup-shaped macrocyclic framework ideal for molecular recognition. This scaffold features four phenolic units linked by methylene bridges, creating a tunable cavity that selectively binds cations and neutral molecules. Its modular design enables functionalization at the upper and lower rims, enhancing guest affinity and solubility in organic and aqueous media. The structure exhibits high stability under standard handling conditions.

Application

Calix(4)arene serves as a versatile macrocyclic scaffold for supramolecular chemistry, enabling selective guest binding through tunable cavity size and functionalized upper/lower rims. Its structural rigidity and modular derivatization facilitate applications in ion recognition, catalysis, and host-guest systems, with demonstrated stability and ease of purification in bench-scale synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   80.92
  • LogP   5.1856
  • H_Acceptors   4
  • H_Donors   4
  • Rotatable_Bonds   0

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