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(S)-2-Amino-3-((tert-butoxycarbonyl)amino)propanoic acid

  • CAS No. 74536-29-1

  • Cat. No. CS-0019469
  • Molecule weightNone
  • Purity≥96%
  • MDL No.MFCD02683451

*For research and further manufacturing use only, not for direct human use.

(S)-2-Amino-3-((tert-butoxycarbonyl)amino)propanoic acid|CS-0019469

Structure of 74536-29-1

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General Information

  • CAS No. 74536-29-1
  • Cat. No. CS-0019469
  • Purity ≥96%
  • MDL No. MFCD02683451
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆N₂O₄
  • Molecular Weight None
  • Synonym(s) N-β-t-Butoxycarbonyl-L-α,β-diaminopropionic acid
  • SMILES N[C@@H](CNC(OC(C)(C)C)=O)C(O)=O

Description

(S)-2-Amino-3-((tert-butoxycarbonyl)amino)propanoic acid is a chiral building block featuring a protected α-amino group and a stereodefined (S)-configuration. This bench-stable derivative enables direct incorporation into peptide synthesis workflows, where the tert-butyl carbamate moiety provides orthogonal protection for amine functionalities during sequential coupling steps.

Application

(S)-2-Amino-3-((tert-butoxycarbonyl)amino)propanoic acid serves as a key chiral building block in peptide synthesis, offering high enantiomeric purity and stability under standard reaction conditions. The Boc-protected amine enables straightforward coupling protocols, while the carboxylic acid facilitates efficient activation and amide bond formation. Its bench-stable nature and compatibility with diverse protecting group strategies make it ideal for iterative solid-phase and solution-phase peptide assembly.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   101.65
  • LogP   -0.077
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   3

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