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Structure of 745052-92-0
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Triphenyl[(tetrahydro-2H-pyran-4-yl)methyl]phosphonium iodide serves as a stable, moisture-tolerant Wittig reagent precursor. The tetrahydro-2H-pyran-4-yl protecting group enhances solubility and stability in polar solvents, enabling reliable olefination under mild conditions. This phosphonium salt facilitates the synthesis of terminal alkenes with high stereoselectivity, particularly useful in complex molecule assembly where functional group tolerance is critical.
Triphenyl[(tetrahydro-2H-pyran-4-yl)methyl]phosphonium iodide serves as a stable, bench-friendly phosphonium salt enabling efficient Wittig-type olefination reactions. The tetrahydropyranyl protecting group enhances solubility and stability while allowing straightforward deprotection under mild acidic conditions. This reagent facilitates the synthesis of stereodefined alkenes with high functional group tolerance and is particularly useful in complex molecule assembly, including natural product and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: