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CS-W001157 4
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3-Aminopropane-1-sulfonamide

  • CAS No. 74494-51-2

  • Cat. No. CS-0088483
  • Molecule weight138.19
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Aminopropane-1-sulfonamide|CS-0088483

Structure of 74494-51-2

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General Information

  • CAS No. 74494-51-2
  • Cat. No. CS-0088483
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₁₀N₂O₂S
  • Molecular Weight 138.19
  • Synonym(s) 3-Amino-1-propanesulfonamide
  • SMILES NCCCS(=O)(N)=O

Description

3-Aminopropane-1-sulfonamide features a primary amine and sulfonamide group separated by a three-carbon chain, enabling versatile conjugation in bioconjugation and medicinal chemistry. This scaffold delivers enhanced solubility and metabolic stability in aqueous environments, facilitating use in peptide derivatization and probe design.

Application

3-Aminopropane-1-sulfonamide serves as a versatile sulfonamide building block for medicinal chemistry and heterocyclic synthesis. Its primary amine and sulfonamide functionalities enable straightforward derivatization, including amidation, acylation, and cyclization reactions. The compound exhibits good bench stability and facilitates purification via standard ion-exchange chromatography, making it well-suited for iterative synthesis workflows and API intermediate development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   86.18
  • LogP   -1.3763
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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