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Structure of 74483-45-7
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1-(Chloromethyl)-4-(trifluoromethylsulfanyl)benzene features a chloromethyl group flanked by a strongly electron-withdrawing trifluoromethylsulfanyl substituent, enabling selective functionalization in late-stage diversification. This aryl chloride integrates readily into cross-coupling cascades and serves as a stable, moisture-tolerant building block for pharmaceutical intermediates and advanced materials synthesis under standard conditions.
1-(Chloromethyl)-4-(trifluoromethylsulfanyl)benzene serves as a versatile building block in medicinal chemistry and materials synthesis, enabling efficient introduction of both chloromethyl and trifluoromethylthio functional groups. The molecule exhibits robust bench stability and facilitates nucleophilic substitution reactions, particularly with amines and thiols, under mild conditions. Its orthogonal reactivity profile supports modular synthesis of complex scaffolds, including heterocycles and bioactive compounds.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: