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CS-W001157 4
Total: USD 88.00

1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)ethanone

  • CAS No. 741709-58-0

  • Cat. No. CS-0041470
  • Purity≥97%
  • MDL No.MFCD09952047
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)ethanone|CS-0041470

Structure of 741709-58-0

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Description

This boronate-functional pyridyl ketone integrates readily into cross-coupling reactions, offering a stable, bench-ready platform for constructing complex heteroaryl architectures. The tetramethylboronate moiety enables efficient Suzuki-Miyaura coupling, while the acetyl group provides a handle for further derivatization.

Application

1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)ethanone serves as a versatile boronate building block for palladium-catalyzed cross-coupling reactions. The pyridyl ketone moiety enables efficient functionalization at the 4-position, while the stable tetramethylboronate group facilitates mild reaction conditions, excellent functional group tolerance, and straightforward purification—making it ideal for constructing complex heterocyclic scaffolds in medicinal chemistry and materials science applications.

General Information

  • CAS No. 741709-58-0
  • Cat. No. CS-0041470
  • Purity ≥97%
  • MDL No. MFCD09952047
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₈BNO₃
  • Molecular Weight 247.10
  • Synonym(s) 2-ACETYLPYRIDINE-4-BORONIC ACID PINACOL ESTER
  • SMILES CC(C1=NC=CC(B2OC(C)(C)C(C)(C)O2)=C1)=O

Computational Chemistry Data

  • TPSA   48.42
  • LogP   1.5834
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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