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CS-W001157 4
Total: USD 88.00

Glycyl-L-glutamic acid

  • CAS No. 7412-78-4

  • Cat. No. CS-W015416
  • Purity≥95%
  • MDL No.MFCD00008128

*For research and further manufacturing use only, not for direct human use.

Glycyl-L-glutamic acid|CS-W015416

Structure of 7412-78-4

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General Information

  • CAS No. 7412-78-4
  • Cat. No. CS-W015416
  • Purity ≥95%
  • MDL No. MFCD00008128
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₂N₂O₅
  • Molecular Weight 204.18
  • Synonym(s) H-Gly-Glu-OH; Gly-Glu
  • SMILES O=C(O)CC[C@@H](C(O)=O)NC(CN)=O

Description

Glycyl-L-glutamic acid features a peptide linkage between glycine and glutamic acid, offering a stable, water-soluble scaffold for bioconjugation. The carboxylic acid side chain of glutamic acid enables facile derivatization, while the terminal amine supports coupling reactions. This dipeptide serves as a building block in peptide synthesis and drug delivery systems requiring polar, biocompatible linkers.

Application

Glycyl-L-glutamic acid serves as a key dipeptide building block for peptide synthesis, offering defined N-terminal glycine and C-terminal glutamic acid functionality. Its stability under standard coupling conditions and compatibility with common protecting groups enable reliable incorporation into larger peptide sequences. The γ-carboxylic acid side chain facilitates orthogonal derivatization and is well-suited for applications in bioconjugation and peptidomimetic design.

Synthesis

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    • In-stock
      Glycyl-L-glutamic acid|CS-W015416
      7412-78-4

    References

    • J. Gen. Chem. USSR (Engl. Transl.), , vol. 51, # 9 p. 1964 - 1971,1690 - 1695
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      121704-20-9
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    • In-stock
      Glycyl-L-glutamic acid|CS-W015416
      7412-78-4

    References

    • Justus Liebigs Annalen der Chemie, , vol. 365, p. 193,199
  • Route3
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      100100-97-8
    • ~%
    • In-stock
      Glycyl-L-glutamic acid|CS-W015416
      7412-78-4

    References

    • Helvetica Chimica Acta, , vol. 29, p. 1128,1130

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   129.72
  • LogP   -1.6207
  • H_Acceptors   4
  • H_Donors   4
  • Rotatable_Bonds   6

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