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CS-W001157 4
Total: USD 88.00

Methyl 2-methylpyrimidine-4-carboxylate

  • CAS No. 73955-55-2

  • Cat. No. CS-0045730
  • Purity≥98%
  • MDL No.MFCD13174780

*For research and further manufacturing use only, not for direct human use.

Methyl 2-methylpyrimidine-4-carboxylate|CS-0045730

Structure of 73955-55-2

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General Information

  • CAS No. 73955-55-2
  • Cat. No. CS-0045730
  • Purity ≥98%
  • MDL No. MFCD13174780
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈N₂O₂
  • Molecular Weight 152.15
  • Synonym(s) None
  • SMILES O=C(C1=NC(C)=NC=C1)OC

Description

Methyl 2-methylpyrimidine-4-carboxylate features a pyrimidine core with strategically positioned methyl and ester groups, enabling direct incorporation into heterocyclic scaffolds. This bench-stable reagent facilitates efficient synthesis of bioactive molecules through palladium-catalyzed cross-coupling and functionalization reactions.

Application

Methyl 2-methylpyrimidine-4-carboxylate serves as a versatile building block in medicinal and synthetic chemistry, enabling efficient access to pyrimidine-based scaffolds. Its methyl and ester functionalities offer orthogonal reactivity for further derivatization, including nucleophilic substitution, hydrogenation, and coupling reactions. The compound exhibits good bench stability and is readily purified by standard chromatographic methods, facilitating integration into multi-step synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   52.08
  • LogP   0.57162
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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