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CS-W001157 4
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Octanohydroxamic acid

  • CAS No. 7377-03-9

  • Cat. No. CS-W001857
  • Molecule weight159.23
  • Purity≥96%
  • MDL No.MFCD00143918

*For research and further manufacturing use only, not for direct human use.

Octanohydroxamic acid|CS-W001857

Structure of 7377-03-9

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General Information

  • CAS No. 7377-03-9
  • Cat. No. CS-W001857
  • Purity ≥96%
  • MDL No. MFCD00143918
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₇NO₂
  • Molecular Weight 159.23
  • Synonym(s) N-Hydroxyoctanamide; Caprylhydroxamic acid
  • SMILES O=C(CCCCCCC)NO

Description

Octanohydroxamic acid features a long aliphatic chain terminating in a hydroxamic acid functional group, offering enhanced lipophilicity for membrane-permeable applications. This structure enables strong metal chelation, particularly with transition metals, while maintaining stability under standard handling conditions.

Application

Octanohydroxamic acid serves as a versatile bifunctional building block for the synthesis of amide and oxime derivatives. Its linear aliphatic chain enables compatibility with diverse coupling protocols, while the hydroxamic acid group facilitates metal chelation and acts as a key handle in bioconjugation and enzyme inhibition studies. The compound exhibits good bench stability and ease of purification, making it suitable for iterative synthetic workflows in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • Monatshefte fur Chemie, , vol. 131, # 6 p. 549 - 569
  • Route2

    References

    • Nippon Nogei Kagaku Kaishi, , vol. 16, p. 504 Bl.agric.chem.Soc.Chem.Abstr., , vol. 16, p. 100 Bl.agric.chem.Soc.Chem.Abstr., , p. 730
  • Route3
    • 1-Nitrooctane|CS-0525115
      629-37-8
    • ~84%
    • In-stock
      Octanohydroxamic acid|CS-W001857
      7377-03-9

    References

    • Journal of Organic Chemistry, , vol. 47, # 27 p. 5283 - 5289

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H313-H350-H360-H410
Precautionary Statements : P264-P270-P273-P280-P330-P391-P405-P501

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   1.8523
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   6

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