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CS-W001157 4
Total: USD 88.00

Fmoc-Ser-Obzl

  • CAS No. 73724-46-6

  • Cat. No. CS-W022731
  • Molecule weight417.45
  • Purity≥96%
  • MDL No.MFCD09752867

*For research and further manufacturing use only, not for direct human use.

Fmoc-Ser-Obzl|CS-W022731

Structure of 73724-46-6

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General Information

  • CAS No. 73724-46-6
  • Cat. No. CS-W022731
  • Purity ≥96%
  • MDL No. MFCD09752867
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₅H₂₃NO₅
  • Molecular Weight 417.45
  • Synonym(s) None
  • SMILES O=C(OCC1=CC=CC=C1)[C@@H](NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O)CO

Description

Fmoc-Ser-Obzl features a protected serine residue with a fluorenylmethoxycarbonyl (Fmoc) group at the N-terminus and a benzyl ester (Obzl) at the C-terminus. This dual protection enables stable incorporation into solid-phase peptide synthesis, where the Fmoc group permits orthogonal deprotection under mild basic conditions, while the Obzl ester supports efficient coupling and subsequent cleavage. The structure combines high solubility in organic solvents with robust stability under standard bench handling, streamlining workflow integration for synthetic peptide chemists.

Application

Fmoc-Ser-Obzl serves as a cornerstone building block in peptide synthesis, enabling efficient N-terminal protection and side-chain stabilization of serine residues. Its benzyl ester group facilitates clean deprotection under standard conditions, while the Fmoc moiety ensures orthogonal handling in automated and manual workflows. The robust stability under ambient conditions simplifies storage and handling, and the structure supports high-yielding coupling reactions with minimal racemization, making it ideal for synthesizing complex peptide sequences and bioactive oligomers.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   84.86
  • LogP   3.6294
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   7

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