2-Bromo-N-(2-fluorophenyl)acetamide

Name: 2-Bromo-N-(2-fluorophenyl)acetamide
Brand: ChemScene
Availability: InStock
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CAS No. 73383-95-6
Cat. No. CS-0186593
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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2-Bromo-N-(2-fluorophenyl)acetamide|CS-0186593

Structure of 73383-95-6

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Description

2-Bromo-N-(2-fluorophenyl)acetamide features a bromine atom at the alpha position of an acetamide scaffold, flanked by a fluorinated phenyl group. This electron-deficient aryl moiety enhances reactivity in cross-coupling processes, while the bench-stable amide linkage supports efficient incorporation into complex molecular architectures under standard conditions.

Application

2-Bromo-N-(2-fluorophenyl)acetamide serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds via cyclization reactions. Its bromine atom facilitates palladium-catalyzed cross-coupling processes, while the amide functionality offers compatibility with diverse functional groups. The molecule exhibits good bench stability and ease of purification, making it well-suited for iterative synthesis workflows in API development.

General Information

CAS No. 73383-95-6
Cat. No. CS-0186593
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₇BrFNO
Molecular Weight 232.05
Synonym(s) 2-BROMO-N-(2-FLUORO-PHENYL)-ACETAMIDE
SMILES C1=CC(=C(C=C1)NC(=O)CBr)F

Computational Chemistry Data

TPSA 29.1
LogP 2.1591
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Amide

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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2-Bromo-N-(2-fluorophenyl)acetamide

CAS No. 73383-95-6

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