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tert-Butyl 2,3-dihydro-1H-pyrrole-1-carboxylate

  • CAS No. 73286-71-2

  • Cat. No. CS-0038328
  • Purity≥95%
  • MDL No.MFCD03839942

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 2,3-dihydro-1H-pyrrole-1-carboxylate|CS-0038328

Structure of 73286-71-2

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General Information

  • CAS No. 73286-71-2
  • Cat. No. CS-0038328
  • Purity ≥95%
  • MDL No. MFCD03839942
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₅NO₂
  • Molecular Weight 169.22
  • Synonym(s) tert-butyl 2,3-dihydropyrrole-1-carboxylate
  • SMILES CC(C)(C)OC(=O)N1C=CCC1

Description

tert-Butyl 2,3-dihydro-1H-pyrrole-1-carboxylate serves as a stable, bench-ready scaffold for constructing nitrogen-containing heterocycles. The protected pyrrolidine moiety enables straightforward incorporation into complex molecular architectures, particularly in medicinal chemistry and natural product synthesis. This derivative combines enhanced solubility with reliable handling under standard conditions.

Synthesis

  • Route1

    References

    • GEORGIA TECH RESEARCH CORPORATION Patent: WO2005/80353 A1, 2005 ; Location in patent: Page/Page column 30 ; WO 2005/080353 A1
  • Route2

    References

    • Oliveira, Denilson F.; Miranda, Paulo C. M. L.; Correia, Carlos R. D. Journal of Organic Chemistry, 1999 , vol. 64, # 18 p. 6646 - 6652
  • Route3

    References

    • Yu, Jurong; Truc, Vu; Riebel, Peter; Hierl, Elizabeth; Mudryk, Boguslaw Tetrahedron Letters, 2005 , vol. 46, # 23 p. 4011 - 4013

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS09
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H227-H301-H315-H319-H335-H410
Precautionary Statements : P210-P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P362-P370+P378-P391-P405-P501

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Computational Chemistry Data

  • TPSA   29.54
  • LogP   2.1409
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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