L-α-aminobutyramide

Name: L-α-aminobutyramide
Brand: ChemScene
Availability: InStock
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CAS No. 7324-11-0
Cat. No. CS-0011803
Purity≥97%
MDL No.MFCD00136552

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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General Information

CAS No. 7324-11-0
Cat. No. CS-0011803
Purity ≥97%
MDL No. MFCD00136552
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₁₀N₂O
Molecular Weight 102.14
Synonym(s) (S)-2-Aminobutanamide; (S)-2-Aminobutyramide; L-2-Amino-n-butanamide; 2-Aminobutanamide
SMILES CC[C@H](N)C(N)=O

Description

L-α-aminobutyramide features a chiral α-amino acid backbone with a primary amide functionality, offering enhanced solubility and metabolic stability. This derivative integrates readily into peptide sequences, serving as a structural analog for alanine in synthetic biology and medicinal chemistry applications.

Application

L-α-Aminobutyramide serves as a valuable chiral building block in peptide synthesis and medicinal chemistry, offering a stable α-amino acid scaffold with orthogonal functionality. Its amide group enables direct incorporation into peptidomimetics, while the α-amino functionality supports standard coupling protocols. The molecule exhibits favorable bench stability and facilitates efficient purification, making it well-suited for iterative synthetic sequences and API intermediate development.

Synthesis

Route1
- In-stock
  
  7682-18-0
- ~77%
- In-stock
  
  7324-11-0
References
- Hildenbrand, Simone; Baqi, Younis; Mueller, Christa E. Journal of Labelled Compounds and Radiopharmaceuticals, 2012 , vol. 55, # 1 p. 48 - 51
Route2
- 53726-14-0
- ~%
- In-stock
  
  7324-11-0
References
- WO2005/28435 A1, ; Page/Page column 9-10 ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 3259
Class : 8	Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 69.11
LogP -0.791
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Amide

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Fatty chain compounds

Key Words

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L-α-aminobutyramide

CAS No. 7324-11-0

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