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CS-W001157 4
Total: USD 88.00

2,8-Dimethylnonane-4,6-dione

  • CAS No. 7307-08-6

  • Cat. No. CS-0154255
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,8-Dimethylnonane-4,6-dione|CS-0154255

Structure of 7307-08-6

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General Information

  • CAS No. 7307-08-6
  • Cat. No. CS-0154255
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₀O₂
  • Molecular Weight 184.28
  • Synonym(s) Diisovalerylmethane
  • SMILES CC(C)CC(=O)CC(=O)CC(C)C

Description

This diketone features two methyl groups at the 2- and 8-positions, enhancing steric shielding around the conjugated enone system. The para-dicarbonyl framework enables facile cyclization and metal coordination, supporting its utility in asymmetric synthesis and ligand design.

Application

2,8-Dimethylnonane-4,6-dione serves as a versatile β-diketone scaffold for constructing substituted heterocycles and complex carbocyclic systems. Its well-defined enolizable α-protons enable controlled aldol condensations and metal-catalyzed cyclizations. The molecule exhibits bench stability, facilitates straightforward purification via recrystallization, and demonstrates broad functional group tolerance in standard synthetic workflows.

Synthesis

  • Route1
    • null|null
      107977-25-3
    • ~56%
    • In-stock
      2,8-Dimethylnonane-4,6-dione|CS-0154255
      7307-08-6

    References

    • Tanaka, Masakazu; Imai, Masanori; Fujio, Masakazu; Sakamoto, Eishi; Takahashi, Miyuki; Eto-Kato, Yasuko; Wu, Xiao Ming; Funakoshi, Kazuhisa; Sakai, Kiyoshi; Suemune, Hiroshi Journal of Organic Chemistry, 2000 , vol. 65, # 18 p. 5806 - 5816
  • Route2
    • null|null
      556-24-1
    • null|null
      108-10-1
    • ~33%
    • In-stock
      2,8-Dimethylnonane-4,6-dione|CS-0154255
      7307-08-6

    References

    • Nandurkar, Nitin S.; Bhanushali, Mayur J.; Patil, Dinkar S.; Bhanage, Bhalchandra M. Synthetic Communications, 2007 , vol. 37, # 23 p. 4111 - 4115
  • Route3
    • null|null
      108-64-5
    • null|null
      108-10-1
    • ~%
    • In-stock
      2,8-Dimethylnonane-4,6-dione|CS-0154255
      7307-08-6

    References

    • Swamer; Hauser Journal of the American Chemical Society, 1950 , vol. 72, p. 1352,1353, 1356

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   34.14
  • LogP   2.6069
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   6

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