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CS-W001157 4
Total: USD 88.00

5-(4-Chlorophenyl)thiazol-2-amine

  • CAS No. 73040-66-1

  • Cat. No. CS-W022247
  • Purity≥95%
  • MDL No.MFCD12779839

*For research and further manufacturing use only, not for direct human use.

5-(4-Chlorophenyl)thiazol-2-amine|CS-W022247

Structure of 73040-66-1

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General Information

  • CAS No. 73040-66-1
  • Cat. No. CS-W022247
  • Purity ≥95%
  • MDL No. MFCD12779839
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇ClN₂S
  • Molecular Weight 210.68
  • Synonym(s) 5-(4-Chlorophenyl)-2-thiazolamine
  • SMILES NC1=NC=C(S1)C1=CC=C(Cl)C=C1

Description

5-(4-Chlorophenyl)thiazol-2-amine features a thiazole core bearing a para-chlorophenyl substituent and an amino group at the 2-position, delivering enhanced electron density and improved solubility in polar solvents. This scaffold serves as a key building block for bioactive heterocycles in medicinal chemistry and materials science applications.

Application

5-(4-Chlorophenyl)thiazol-2-amine serves as a versatile building block in medicinal chemistry, enabling the synthesis of thiazole-based heterocycles with established utility in kinase inhibitor and antimicrobial scaffold development. Its robust bench stability, compatibility with standard coupling reactions, and tolerance to diverse functional groups facilitate efficient incorporation into complex molecular architectures.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   3.0457
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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