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CS-W001157 4
Total: USD 88.00

Melatonin

  • CAS No. 73-31-4

  • Cat. No. CS-1769
  • Purity≥98%
  • MDL No.MFCD00005655

*For research and further manufacturing use only, not for direct human use.

Melatonin|CS-1769

Structure of 73-31-4

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General Information

  • CAS No. 73-31-4
  • Cat. No. CS-1769
  • Purity ≥98%
  • MDL No. MFCD00005655
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₆N₂O₂
  • Molecular Weight 232.28
  • Synonym(s) N-Acetyl-5-methoxytryptamine
  • SMILES CC(NCCC1=CNC2=C1C=C(OC)C=C2)=O

Description

This compound has been used as a building block in a variety of synthetic reactions.

Application

Melatonin serves as a well-established indole-based neurohormone and chronobiotic agent, enabling precise modulation of circadian rhythms in preclinical and clinical research. Its functional indole core facilitates selective receptor binding and exhibits favorable bench stability, ease of handling, and compatibility with standard purification methods. Widely utilized in sleep regulation studies and oxidative stress assays, Melatonin functions as a reliable building block for bioactive heterocyclic scaffolds and provides consistent performance across diverse physiological models.

Synthesis

  • Route1
    • In-stock
      5-Methoxytryptamine|CS-W015885
      608-07-1
    • null|null
      108-24-7
    • ~98%
    • In-stock
      Melatonin|CS-1769
      73-31-4

    References

    • Prabhakar; Kumar, N. Vasanth; Reddy, M. Ravikanth; Sarma; Reddy, G. Om Organic Process Research and Development, 1999 , vol. 3, # 3 p. 155 - 160
  • Route2
    • In-stock
      N-Acetyl-5-hydroxytryptamine|CS-0030736
      1210-83-9
    • null|null
      77-78-1
    • ~61%
    • In-stock
      Melatonin|CS-1769
      73-31-4

    References

    • HERCULES TECHNOLOGY MANAGEMENT CO V, INC.; BLAGG, Julian Patent: WO2011/47156 A1, 2011 ; Location in patent: Page/Page column 39 ; WO 2011/047156 A1
  • Route3
    • N-(Prop-2-en-1-yl)acetamide|CS-0224602
      692-33-1
    • null|null
      201230-82-2
    • In-stock
      (4-Methoxyphenyl)hydrazine monohydrochloride|CS-W007694
      19501-58-7
    • ~43%
    • In-stock
      Melatonin|CS-1769
      73-31-4

    References

    • Verspui, Goeran; Elbertse, Guido; Sheldon, Frank A.; Hacking, Michiel A. P. J.; Sheldon, Roger A. Chemical Communications, 2000 , # 15 p. 1363 - 1364

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H341-H361
Precautionary Statements : P202-P280-P308+P313-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   54.12
  • LogP   1.8551
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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