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CS-W001157 4
Total: USD 88.00

1-(m-Tolyl)ethanol

  • CAS No. 7287-81-2

  • Cat. No. CS-0153227
  • Purity≥98%
  • MDL No.MFCD00046635

*For research and further manufacturing use only, not for direct human use.

1-(m-Tolyl)ethanol|CS-0153227

Structure of 7287-81-2

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General Information

  • CAS No. 7287-81-2
  • Cat. No. CS-0153227
  • Purity ≥98%
  • MDL No. MFCD00046635
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂O
  • Molecular Weight 136.19
  • Synonym(s) 1-(3-Methylphenyl)ethanol
  • SMILES CC1=CC(=CC=C1)C(C)O

Description

1-(m-Tolyl)ethanol is a bench-stable, moisture-tolerant aryl alcohol featuring a para-methylphenyl group that enhances electron density at the benzylic position. This structure enables direct functionalization in cross-coupling reactions and serves as a robust chiral auxiliary scaffold in asymmetric synthesis workflows.

Application

1-(m-Tolyl)ethanol serves as a versatile chiral building block in synthetic organic chemistry, enabling access to pharmaceutically relevant arylalkyl scaffolds. Its bench-stable nature and compatibility with standard functional group transformations facilitate straightforward derivatization. The molecule functions effectively in asymmetric synthesis and catalytic reductions, offering predictable stereocontrol and ease of purification.

Synthesis

  • Route1
    • 3'-Methylacetophenone Celecoxib  Impurity|CS-0229272
      585-74-0
    • ~98%
    • In-stock
      1-(m-Tolyl)ethanol|CS-0153227
      7287-81-2

    References

    • Du, Wangming; Wang, Liandi; Wu, Ping; Yu, Zhengkun Chemistry - A European Journal, 2012 , vol. 18, # 37 p. 11550 - 11554
  • Route2
    • null|null
      766-82-5
    • ~82%
    • In-stock
      1-(m-Tolyl)ethanol|CS-0153227
      7287-81-2

    References

    • Li, Le; Herzon, Seth B. Journal of the American Chemical Society, 2012 , vol. 134, # 42 p. 17376 - 17379,4 Title/Abstract Show Details Li, Le; Herzon, Seth B. Journal of the American Chemical Society, 2012 , vol. 134, # 42 p. 17376 - 17379
  • Route3
    • null|null
      58276-67-8
    • ~%
    • In-stock
      1-(m-Tolyl)ethanol|CS-0153227
      7287-81-2

    References

    • Yamamoto, Takeshi; Suginome, Michinori Angewandte Chemie - International Edition, 2009 , vol. 48, # 3 p. 539 - 542

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.04832
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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