Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-{[(4-chlorophenyl)methyl]sulfanyl}-1,3,4-thiadiazol-2-amine

  • CAS No. 72836-33-0

  • Cat. No. CS-0218918
  • Molecule weight257.76
  • Purity95+%
  • MDL No.MFCD00114062

*For research and further manufacturing use only, not for direct human use.

5-{[(4-chlorophenyl)methyl]sulfanyl}-1,3,4-thiadiazol-2-amine|CS-0218918

Structure of 72836-33-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 72836-33-0
  • Cat. No. CS-0218918
  • Purity 95+%
  • MDL No. MFCD00114062
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈ClN₃S₂
  • Molecular Weight 257.76
  • Synonym(s) 2-Amino-5-[(4-chlorobenzyl)thio]-1,3,4-thiadiazole
  • SMILES NC1=NN=C(SCC2=CC=C(Cl)C=C2)S1

Description

Inhibiting RegA DNA-binding via conserved HTH domain interactions, Regacin (CAS 72836-33-0) disrupts virulence gene activation in Enterobacteriaceae by targeting W188 and R223 residues, suppressing colonization in murine models without altering dimerization. (24 words)

Synthesis

  • Route1
    • null|null
      104-83-6
    • 5-Amino-1,3,4-thiadiazole-2(3H)-thione Acetazolamide Impurity|CS-0229575
      2349-67-9
    • ~90%
    • null|null
      112589-14-7
    • 5-{[(4-chlorophenyl)methyl]sulfanyl}-1,3,4-thiadiazol-2-amine|CS-0218918
      72836-33-0

    References

    • KUMIAI CHEMICAL INDUSTRY CO., LTD.; IHARA CHEMICAL INDUSTRY Co., Ltd. Patent: EP282635 A3, 1989 ;
  • Route2

    References

    • Ling, Yong; Chen, Guang Tong; Wang, Dong Geng; Li, Yu Qin; Wang, Xin Yang; Xiao, You An; Zheng, Heng Chinese Chemical Letters, 2012 , vol. 23, # 10 p. 1141 - 1144,4
  • Route3
    • null|null
      104-83-6
    • 5-Amino-1,3,4-thiadiazole-2(3H)-thione Acetazolamide Impurity|CS-0229575
      2349-67-9
    • ~66%
    • 5-{[(4-chlorophenyl)methyl]sulfanyl}-1,3,4-thiadiazol-2-amine|CS-0218918
      72836-33-0

    References

    • Clerici; Pocar; Guido; Loche; Perlini; Brufani Journal of Medicinal Chemistry, 2001 , vol. 44, # 6 p. 931 - 936

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   51.8
  • LogP   3.066
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   3

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 72836-33-0 sigma72836-33-0 manufacturer72836-33-0 price72836-33-0 structure72836-33-0 SDSbuy 72836-33-072836-33-0 supplier72836-33-0 uses72836-33-0 molecular weightprice of 72836-33-072836-33-0 chemical name formula of 72836-33-0
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label