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CS-W001157 4
Total: USD 88.00

Thiazole-2,4-diamine hydrochloride

  • CAS No. 72792-54-2

  • Cat. No. CS-W006972
  • Molecule weight151.62
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Thiazole-2,4-diamine hydrochloride|CS-W006972

Structure of 72792-54-2

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General Information

  • CAS No. 72792-54-2
  • Cat. No. CS-W006972
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₆ClN₃S
  • Molecular Weight 151.62
  • Synonym(s) 1,3-thiazole-2,4-diamine
  • SMILES NC1=NC(N)=CS1.Cl

Description

Thiazole-2,4-diamine hydrochloride offers a bench-stable, moisture-tolerant platform for heterocyclic synthesis. The dual amine functionality enables straightforward coupling reactions and functionalization at both positions. This compound integrates readily into pharmaceutical intermediates and advanced materials, providing access to electron-rich scaffolds with enhanced solubility and reactivity under standard conditions.

Application

Thiazole-2,4-diamine hydrochloride serves as a versatile building block in medicinal chemistry, enabling the synthesis of thiazole-based heterocycles through standard coupling and cyclization protocols. Its dual amine functionality offers orthogonal reactivity for derivatization, while the hydrochloride salt enhances bench stability and solubility in polar solvents. This compound functions effectively in amide bond formation, Ullmann-type couplings, and scaffold elaboration for API candidates targeting kinase inhibition and antimicrobial activity.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   64.93
  • LogP   0.7293
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   0

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