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CS-W001157 4
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(5-Methoxypyrazin-2-yl)methanol

  • CAS No. 72788-88-6

  • Cat. No. CS-0043604
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(5-Methoxypyrazin-2-yl)methanol|CS-0043604

Structure of 72788-88-6

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General Information

  • CAS No. 72788-88-6
  • Cat. No. CS-0043604
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂O₂
  • Molecular Weight 140.14
  • Synonym(s) 5-Methoxy-2-pyrazinemethanol
  • SMILES OCC1=NC=C(OC)N=C1

Description

This bench-stable alcohol features a 5-methoxypyrazin-2-yl scaffold, offering a polar, electron-deficient heterocyclic platform. The pendant hydroxymethyl group enables direct functionalization or conjugation, facilitating integration into bioactive molecules and synthetic intermediates requiring tailored solubility and electronic properties.

Application

(5-Methoxypyrazin-2-yl)methanol serves as a versatile building block for pyrazine-based heterocycles, enabling efficient functionalization in medicinal chemistry and agrochemical synthesis. The aldehyde functionality facilitates reductive amination, Grignard additions, and coupling reactions with nucleophiles, while the methoxy group enhances solubility and modulates electronic properties. Bench-stable and compatible with standard purification methods, it functions reliably in multi-step sequences requiring orthogonal reactivity.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.24
  • LogP   -0.0225
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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