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Structure of 72678-19-4
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2,6-Dibromo-4-(trifluoromethyl)aniline features a trifluoromethyl group flanked by two bromine substituents at the 2 and 6 positions, creating a highly electron-deficient aromatic core. This configuration enhances its utility in palladium-catalyzed cross-coupling reactions, enabling efficient construction of complex heterocycles and functionalized biaryls under standard conditions. The molecule exhibits excellent bench stability and moisture tolerance, simplifying handling in synthetic workflows.
2,6-Dibromo-4-(trifluoromethyl)aniline serves as a versatile building block for brominated aromatic scaffolds in medicinal chemistry and materials science. Its ortho-bromine substituents enable palladium-catalyzed cross-coupling reactions, while the trifluoromethyl group imparts enhanced metabolic stability and lipophilicity. The molecule exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis of complex heterocycles and functionalized arenes.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: