Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2,6-Dibromo-4-(trifluoromethyl)aniline

  • CAS No. 72678-19-4

  • Cat. No. CS-0157746
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,6-Dibromo-4-(trifluoromethyl)aniline|CS-0157746

Structure of 72678-19-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 72678-19-4
  • Cat. No. CS-0157746
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄Br₂F₃N
  • Molecular Weight 318.92
  • Synonym(s) 4-Amino-3,5-dibromobenzotrifluoride
  • SMILES C1=C(C=C(C(=C1Br)N)Br)C(F)(F)F

Description

2,6-Dibromo-4-(trifluoromethyl)aniline features a trifluoromethyl group flanked by two bromine substituents at the 2 and 6 positions, creating a highly electron-deficient aromatic core. This configuration enhances its utility in palladium-catalyzed cross-coupling reactions, enabling efficient construction of complex heterocycles and functionalized biaryls under standard conditions. The molecule exhibits excellent bench stability and moisture tolerance, simplifying handling in synthetic workflows.

Application

2,6-Dibromo-4-(trifluoromethyl)aniline serves as a versatile building block for brominated aromatic scaffolds in medicinal chemistry and materials science. Its ortho-bromine substituents enable palladium-catalyzed cross-coupling reactions, while the trifluoromethyl group imparts enhanced metabolic stability and lipophilicity. The molecule exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis of complex heterocycles and functionalized arenes.

Synthesis

  • Route1
    • 4-(Trifluoromethyl)aniline Leflunomide Impurity|CS-0229655
      455-14-1
    • ~91%
    • In-stock
      2,6-Dibromo-4-(trifluoromethyl)aniline|CS-0157746
      72678-19-4

    References

    • Podgorsek, Ajda; Stavber, Stojan; Zupan, Marko; Iskra, Jernej Tetrahedron, 2009 , vol. 65, # 22 p. 4429 - 4439
  • Route2

    References

    • Tetrahedron, , vol. 65, # 22 p. 4429 - 4439

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   26.02
  • LogP   3.8126
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2,6-Dibromo-4-(trifluoromethyl)aniline sigma2,6-Dibromo-4-(trifluoromethyl)aniline manufacturer2,6-Dibromo-4-(trifluoromethyl)aniline price2,6-Dibromo-4-(trifluoromethyl)aniline structure2,6-Dibromo-4-(trifluoromethyl)aniline SDSbuy 2,6-Dibromo-4-(trifluoromethyl)aniline2,6-Dibromo-4-(trifluoromethyl)aniline supplier2,6-Dibromo-4-(trifluoromethyl)aniline uses2,6-Dibromo-4-(trifluoromethyl)aniline molecular weightprice of 2,6-Dibromo-4-(trifluoromethyl)aniline2,6-Dibromo-4-(trifluoromethyl)aniline chemical name formula of 2,6-Dibromo-4-(trifluoromethyl)aniline
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label