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CS-W001157 4
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1-(4-Bromo-1H-pyrrol-2-yl)-2,2,2-trichloroethanone

  • CAS No. 72652-32-5

  • Cat. No. CS-0695444
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-(4-Bromo-1H-pyrrol-2-yl)-2,2,2-trichloroethanone|CS-0695444

Structure of 72652-32-5

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General Information

  • CAS No. 72652-32-5
  • Cat. No. CS-0695444
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃BrCl₃NO
  • Molecular Weight 291.36
  • Synonym(s) None
  • SMILES ClC(Cl)(Cl)C(=O)C1=CC(Br)=CN1

Description

This trichloroacetophenone derivative features a bromopyrrole moiety that enables direct functionalization in cross-coupling reactions. The electron-deficient ketone group facilitates nucleophilic addition, while the trifluoromethyl-like steric and electronic profile enhances stability under standard conditions.

Application

1-(4-Bromo-1H-pyrrol-2-yl)-2,2,2-trichloroethanone serves as a versatile building block for constructing brominated heterocyclic scaffolds. Its trichloromethyl group enables efficient functionalization via nucleophilic substitution or reduction, while the pyrrole ring provides a platform for further derivatization. The molecule exhibits bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   N/A
  • LogP   N/A
  • H_Acceptors   N/A
  • H_Donors   N/A
  • Rotatable_Bonds   N/A

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