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Structure of 726139-60-2
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Ethyl 2-(pyrrolidin-3-yl)acetate hydrochloride features a pyrrolidin-3-yl moiety that enhances solubility and metabolic stability. This zwitterionic form facilitates efficient incorporation into peptide-like scaffolds, offering improved bioavailability in synthetic intermediates for medicinal chemistry applications.
Ethyl 2-(pyrrolidin-3-yl)acetate hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrrolidine-containing scaffolds via standard functional group transformations. The hydrochloride salt enhances bench stability and solubility, facilitating handling and purification. It functions as a key intermediate in the synthesis of bioactive molecules, particularly those incorporating γ-aminobutyric acid (GABA) analogs or heterocyclic pharmacophores, with demonstrated compatibility in coupling reactions and reductive amination protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: