Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Amino-2-methoxybenzonitrile

  • CAS No. 7251-09-4

  • Cat. No. CS-W006863
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Amino-2-methoxybenzonitrile|CS-W006863

Structure of 7251-09-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 7251-09-4
  • Cat. No. CS-W006863
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈N₂O
  • Molecular Weight 148.16
  • Synonym(s) 5-Amino-2-cyanoanisole
  • SMILES N#CC1=CC=C(N)C=C1OC

Description

2-Hydroxyphenylacetic Acid is an intermediate in the synthesis of atenolol and 3,4-dihydroxyphenylacetic acid.

Application

4-Amino-2-methoxybenzonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted benzimidazoles and other heterocyclic scaffolds. Its complementary amino, methoxy, and nitrile functionalities offer orthogonal reactivity for sequential functionalization, with excellent bench stability and straightforward purification. The molecule functions reliably in standard coupling and cyclization protocols, facilitating rapid diversification in lead optimization campaigns.

Synthesis

  • Route1

    References

    • Synthesis, , # 19 p. 3316 - 3340
  • Route2

    References

    • Journal of Medicinal Chemistry, , vol. 44, # 23 p. 3856 - 3871
  • Route3
    • null|null
      536-90-3
    • ~%
    • In-stock
      4-Amino-2-methoxybenzonitrile|CS-W006863
      7251-09-4

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 7 p. 1860 - 1864

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   59.04
  • LogP   1.14908
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Amino-2-methoxybenzonitrile sigma4-Amino-2-methoxybenzonitrile manufacturer4-Amino-2-methoxybenzonitrile price4-Amino-2-methoxybenzonitrile structure4-Amino-2-methoxybenzonitrile SDSbuy 4-Amino-2-methoxybenzonitrile4-Amino-2-methoxybenzonitrile supplier4-Amino-2-methoxybenzonitrile uses4-Amino-2-methoxybenzonitrile molecular weightprice of 4-Amino-2-methoxybenzonitrile4-Amino-2-methoxybenzonitrile chemical name formula of 4-Amino-2-methoxybenzonitrile
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label