4-Methoxypyrimidine-5-carboxylic acid

Name: 4-Methoxypyrimidine-5-carboxylic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 72411-89-3
Cat. No. CS-0043302
Molecule weight154.12
Purity≥96%
MDL No.MFCD20644991

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Methoxypyrimidine-5-carboxylic acid|CS-0043302

Structure of 72411-89-3

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 72411-89-3
Cat. No. CS-0043302
Purity ≥96%
MDL No. MFCD20644991
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₆N₂O₃
Molecular Weight 154.12
Synonym(s) 4-methoxy-5-Pyrimidinecarboxylic acid
SMILES O=C(C1=CN=CN=C1OC)O

Description

4-Methoxypyrimidine-5-carboxylic acid features a pyrimidine core bearing a methoxy group at the 4-position and a carboxylic acid at the 5-position, enabling direct conjugation or derivatization. The electron-withdrawing carboxyl moiety enhances reactivity in coupling processes, while the methoxy substituent provides steric and electronic modulation. This scaffold integrates readily into bioactive molecules and functional materials under standard conditions.

Application

4-Methoxypyrimidine-5-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pyrimidine-based scaffolds relevant in medicinal chemistry. Its dual functionality—electron-withdrawing carboxylic acid and electron-donating methoxy group—facilitates regioselective functionalization and supports diverse coupling reactions. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthetic workflows in API development.

Synthesis

Route1
- 84332-00-3
- ~%
- In-stock
  
  72411-89-3
References
- Dostert; Imbert; Ancher; et al. European Journal of Medicinal Chemistry, 1982 , vol. 17, # 5 p. 437 - 444
Route2
- In-stock
  
  41103-17-7
- ~%
- In-stock
  
  72411-89-3
References
- Dostert; Imbert; Ancher; et al. European Journal of Medicinal Chemistry, 1982 , vol. 17, # 5 p. 437 - 444

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 72.31
LogP 0.1834
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 2

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

4-Methoxypyrimidine-5-carboxylic acid sigma4-Methoxypyrimidine-5-carboxylic acid manufacturer4-Methoxypyrimidine-5-carboxylic acid price4-Methoxypyrimidine-5-carboxylic acid structure4-Methoxypyrimidine-5-carboxylic acid SDSbuy 4-Methoxypyrimidine-5-carboxylic acid4-Methoxypyrimidine-5-carboxylic acid supplier4-Methoxypyrimidine-5-carboxylic acid uses4-Methoxypyrimidine-5-carboxylic acid molecular weightprice of 4-Methoxypyrimidine-5-carboxylic acid4-Methoxypyrimidine-5-carboxylic acid chemical name formula of 4-Methoxypyrimidine-5-carboxylic acid

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-Methoxypyrimidine-5-carboxylic acid

CAS No. 72411-89-3

Recommended Products