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Structure of 72351-36-1
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This azetidinylmethanol derivative features a benzhydryl-protected amine scaffold, offering enhanced stability and solubility in polar solvents. The tertiary alcohol functionality enables direct functionalization or derivatization under mild conditions. This robust, bench-stable building block integrates efficiently into complex molecular architectures for medicinal chemistry applications.
(1-Benzhydrylazetidin-3-yl)methanol serves as a versatile chiral building block for the synthesis of bioactive heterocycles, particularly in medicinal chemistry. Its azetidine core exhibits enhanced metabolic stability and improved membrane permeability compared to larger saturated rings. The benzylic alcohol functionality enables straightforward derivatization—via oxidation, protection, or coupling reactions—facilitating rapid access to diverse analogs. Bench-stable and compatible with standard synthetic workflows, it functions effectively in both small-molecule discovery and API scaffold development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: