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CS-W001157 4
Total: USD 88.00

Ethyl 12-bromododecanoate

  • CAS No. 72338-48-8

  • Cat. No. CS-0187390
  • Purity≥96%
  • MDL No.MFCD30470568

*For research and further manufacturing use only, not for direct human use.

Ethyl 12-bromododecanoate|CS-0187390

Structure of 72338-48-8

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General Information

  • CAS No. 72338-48-8
  • Cat. No. CS-0187390
  • Purity ≥96%
  • MDL No. MFCD30470568
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₇BrO₂
  • Molecular Weight 307.27
  • Synonym(s) None
  • SMILES O=C(OCC)CCCCCCCCCCCBr

Description

Ethyl 12-bromododecanoate features a long aliphatic chain with a terminal bromide and ester functional group, enabling versatile coupling reactions. This bifunctional molecule serves as a key intermediate for synthesizing polymeric materials, surfactants, and specialty chemicals through nucleophilic substitution or transition-metal-catalyzed transformations.

Application

Ethyl 12-bromododecanoate serves as a versatile linear alkyl bromide building block for the synthesis of functionalized fatty acid derivatives and polymeric intermediates. The terminal bromide enables efficient SN2 displacement, enabling chain extension or incorporation into complex architectures. Its ethyl ester group offers stability and facilitates purification, while the aliphatic chain provides compatibility with diverse reaction conditions. This reagent is particularly useful in preparing long-chain analogs for surfactant, lipid, or material science applications.

Synthesis

  • Route1
    • null|null
      78640-13-8
    • ~92%
    • In-stock
      Ethyl 12-bromododecanoate|CS-0187390
      72338-48-8

    References

    • Colorobbia Italia S.p.a. Patent: EP1979365 B1, 2012 ; Location in patent: Page/Page column 9 ;
  • Route2

    References

    • Pawsey, Shane; McCormick, Mark; De Paul, Susan; Graf, Robert; Lee; Reven, Linda; Spiess, Hans W. Journal of the American Chemical Society, 2003 , vol. 125, # 14 p. 4174 - 4184
  • Route3
    • null|null
      64-17-5
    • In-stock
      12-Bromododecanoic acid|CS-0158383
      73367-80-3
    • ~%
    • In-stock
      Ethyl 12-bromododecanoate|CS-0187390
      72338-48-8

    References

    • Houston, Christopher T.; Reilly, James P. Journal of Physical Chemistry A, 2000 , vol. 104, # 45 p. 10383 - 10391

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   4.8454
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   12

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