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CS-W001157 4
Total: USD 88.00

1-(2-Naphthyl)ethanol

  • CAS No. 7228-47-9

  • Cat. No. CS-0186229
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-(2-Naphthyl)ethanol|CS-0186229

Structure of 7228-47-9

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General Information

  • CAS No. 7228-47-9
  • Cat. No. CS-0186229
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₂O
  • Molecular Weight 172.22
  • Synonym(s) α-Methyl-2-naphthalenemethanol
  • SMILES CC(C1=CC2=CC=CC=C2C=C1)O

Description

1-(2-Naphthyl)ethanol is a bench-stable, moisture-tolerant aromatic alcohol featuring a naphthalene ring fused to an ethanolic side chain. This structural motif enables direct integration into synthetic routes for pharmaceutical intermediates and advanced materials. The compound's electron-rich aromatic system facilitates coupling reactions under standard conditions.

Application

1-(2-Naphthyl)ethanol serves as a versatile building block in synthetic organic chemistry, enabling the construction of biaryl and heterocyclic scaffolds through standard coupling and oxidation reactions. Its bench-stable nature and tolerance to diverse functional groups facilitate straightforward incorporation into complex molecular architectures. The molecule functions effectively as a precursor in medicinal chemistry campaigns and process development, particularly where extended π-conjugation or lipophilic character is required.

Synthesis

  • Route1
    • 2-Acetonaphthone, ≥99%|CS-1268986
      93-08-3
    • ~99%
    • In-stock
      1-(2-Naphthyl)ethanol|CS-0186229
      7228-47-9

    References

    • Battilocchio, Claudio; Hawkins, Joel M.; Ley, Steven V. Organic Letters, 2013 , vol. 15, # 9 p. 2278 - 2281
  • Route2

    References

    • Bosson, Johann; Nolan, Steven P. Journal of Organic Chemistry, 2010 , vol. 75, # 6 p. 2039 - 2043
  • Route3

    References

    • Chemical Communications, , # 41 p. 4297 - 4299

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.8931
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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