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Ethyl 2-acetoxycyclopropanecarboxylate

  • CAS No. 72229-07-3

  • Cat. No. CS-0163003
  • Molecule weight172.18
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-acetoxycyclopropanecarboxylate|CS-0163003

Structure of 72229-07-3

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General Information

  • CAS No. 72229-07-3
  • Cat. No. CS-0163003
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂O₄
  • Molecular Weight 172.18
  • Synonym(s) Ethyl 2-(acetyloxy)cyclopropanecarboxylate
  • SMILES O=C(C1C(OC(C)=O)C1)OCC

Description

Ethyl 2-acetoxycyclopropanecarboxylate features a strained cyclopropane ring bearing an acetoxycarbonyl group, enabling direct functionalization in cycloaddition and C–H activation reactions. This bench-stable reagent integrates seamlessly into synthetic sequences requiring controlled ring strain release.

Application

Ethyl 2-acetoxycyclopropanecarboxylate serves as a versatile cyclopropane building block in synthetic organic chemistry, enabling the construction of strained ring systems via stereospecific transformations. Its acetate group provides mild activation for subsequent functionalization, while the ester moiety supports compatibility with standard coupling and reduction protocols. Bench-stable and readily purified by distillation or column chromatography, it functions effectively in asymmetric synthesis and heterocycle formation.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H225-H315-H319
Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P280-P362+P364-P370+P378-P501

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Computational Chemistry Data

  • TPSA   52.6
  • LogP   0.5011
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   3

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