(1R,2S)-2-Amino-1-(Boc-amino)cyclopentane

Name: (1R,2S)-2-Amino-1-(Boc-amino)cyclopentane
Brand: ChemScene
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CAS No. 721395-15-9
Cat. No. CS-0186030
Purity≥98%
MDL No.None

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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(1R,2S)-2-Amino-1-(Boc-amino)cyclopentane|CS-0186030

Structure of 721395-15-9

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Description

This chiral cyclopentane scaffold features a Boc-protected amine and a free amino group, enabling direct coupling or selective deprotection in peptide synthesis. The (1R,2S) stereochemistry ensures high diastereoselectivity in cyclization reactions, while the bench-stable Boc group simplifies handling and purification under standard conditions.

Application

(1R,2S)-2-Amino-1-(Boc-amino)cyclopentane serves as a stereochemically defined building block for the synthesis of cyclopentane-containing bioactive molecules. Its protected diamine motif enables sequential functionalization while maintaining configurational integrity. The Boc group ensures stability during storage and facilitates selective deprotection under mild acidic conditions. This compound functions effectively in peptide coupling, heterocycle formation, and scaffold diversification workflows common in medicinal chemistry and process development.

General Information

CAS No. 721395-15-9
Cat. No. CS-0186030
Purity ≥98%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₂₀N₂O₂
Molecular Weight 200.28
Synonym(s) tert-Butyl ((1R,2S)-2-aminocyclopentyl)carbamate
SMILES CC(C)(OC(N[C@@H]1CCC[C@@H]1N)=O)C

Computational Chemistry Data

TPSA 64.35
LogP 1.3909
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 1

Safety Information

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GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 1759
Class : 8	Packing Group : Ⅲ
Hazard Statements : H315-H318
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Other Classifications

Building Blocks Functional Group Amine

Building Blocks Skeleton Fatty ring compounds Cyclopentane compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(1R,2S)-2-Amino-1-(Boc-amino)cyclopentane

CAS No. 721395-15-9

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