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CS-W001157 4
Total: USD 88.00

4-Amino-5-chloro-2-methoxybenzoic acid

  • CAS No. 7206-70-4

  • Cat. No. CS-0128743
  • Purity≥98%
  • MDL No.MFCD00038794

*For research and further manufacturing use only, not for direct human use.

4-Amino-5-chloro-2-methoxybenzoic acid|CS-0128743

Structure of 7206-70-4

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General Information

  • CAS No. 7206-70-4
  • Cat. No. CS-0128743
  • Purity ≥98%
  • MDL No. MFCD00038794
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈ClNO₃
  • Molecular Weight 201.61
  • Synonym(s) None
  • SMILES O=C(O)C1=CC(Cl)=C(N)C=C1OC

Application

4-Amino-5-chloro-2-methoxybenzoic acid serves as a versatile building block for heterocyclic synthesis and medicinal chemistry campaigns. Its ortho-substituted aromatic core enables efficient coupling reactions, while the amino and carboxylic acid groups provide handles for derivatization. The methoxy and chloro substituents offer predictable electronic modulation and compatibility with standard functional group transformations, facilitating rapid access to diverse scaffolds in API development.

Synthesis

  • Route1

    References

    • Anphar, S.A. Patent: US4138492 A1, 1979 ;
  • Route2

    References

    • WO2005/23808 A2, ; Page/Page column 37-38 ;
  • Route3

    References

    • Ehrenkaufer, Richard L.; Scripko, James G.; Hoffman, Patricia L. Organic Preparations and Procedures International, 1992 , vol. 24, # 1 p. 64 - 66

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   72.55
  • LogP   1.629
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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