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CS-W001157 4
Total: USD 88.00

H-Thr(tBu)-OMe.HCl

  • CAS No. 71989-43-0

  • Cat. No. CS-W022753
  • Molecule weight225.71
  • Purity≥98%
  • MDL No.MFCD00077111

*For research and further manufacturing use only, not for direct human use.

H-Thr(tBu)-OMe.HCl|CS-W022753

Structure of 71989-43-0

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General Information

  • CAS No. 71989-43-0
  • Cat. No. CS-W022753
  • Purity ≥98%
  • MDL No. MFCD00077111
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₂₀ClNO₃
  • Molecular Weight 225.71
  • Synonym(s) None
  • SMILES C[C@@H](OC(C)(C)C)[C@H](N)C(OC)=O.[H]Cl

Description

H-Thr(tBu)-OMe.HCl features a tert-butyl-protected threonine side chain and methyl ester terminus, offering enhanced stability and ease of handling in peptide synthesis. This derivative enables efficient incorporation into sequences requiring protected hydroxy functionality, streamlining downstream deprotection workflows under standard conditions.

Synthesis

  • Route1
    • Methyl N-((benzyloxy)carbonyl)-O-(tert-butyl)-L-threoninate|CS-0539097
      52785-41-8
    • ~89%
    • In-stock
      H-Thr(tBu)-OMe.HCl|CS-W022753
      71989-43-0

    References

    • Prochazka; Jost Collection of Czechoslovak Chemical Communications, 1980 , vol. 45, # 4 p. 1305 - 1314

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   61.55
  • LogP   1.1121
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   3

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