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CS-W001157 4
Total: USD 88.00

1-Ethyl-1H-imidazole-5-carboxylic acid

  • CAS No. 71925-11-6

  • Cat. No. CS-W019208
  • Molecule weight140.14
  • Purity≥95%
  • MDL No.MFCD08445747

*For research and further manufacturing use only, not for direct human use.

1-Ethyl-1H-imidazole-5-carboxylic acid|CS-W019208

Structure of 71925-11-6

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General Information

  • CAS No. 71925-11-6
  • Cat. No. CS-W019208
  • Purity ≥95%
  • MDL No. MFCD08445747
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂O₂
  • Molecular Weight 140.14
  • Synonym(s) 3-ETHYL-3H-IMIDAZOLE-4-CARBOXYLIC ACID
  • SMILES O=C(C1=CN=CN1CC)O

Description

1-Ethyl-1H-imidazole-5-carboxylic acid features a carboxylic acid group conjugated to an electron-deficient imidazole ring, enabling direct incorporation into peptide and heterocyclic scaffolds. This bench-stable derivative offers enhanced solubility in polar solvents and serves as a robust building block for bioconjugation and medicinal chemistry applications.

Application

1-Ethyl-1H-imidazole-5-carboxylic acid serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling efficient access to imidazole-based scaffolds. Its carboxylic acid functionality facilitates amide coupling, esterification, and derivatization under standard conditions, while the ethyl substituent enhances solubility and modulates electronic properties. The molecule exhibits bench stability and compatibility with common purification methods, making it well-suited for iterative synthesis workflows in API development and fragment-based design.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   55.12
  • LogP   0.6012
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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