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CS-W001157 4
Total: USD 88.00

2-Fluoro-4,5-dimethoxybenzaldehyde

  • CAS No. 71924-62-4

  • Cat. No. CS-0128766
  • Purity≥97%
  • MDL No.MFCD00061108

*For research and further manufacturing use only, not for direct human use.

2-Fluoro-4,5-dimethoxybenzaldehyde|CS-0128766

Structure of 71924-62-4

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General Information

  • CAS No. 71924-62-4
  • Cat. No. CS-0128766
  • Purity ≥97%
  • MDL No. MFCD00061108
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉FO₃
  • Molecular Weight 184.16
  • Synonym(s) 6-Fluoroveratraldehyde
  • SMILES O=CC1=CC(OC)=C(OC)C=C1F

Description

This fluorinated benzaldehyde features a strategically positioned para-fluoro group and two methoxy substituents, enabling enhanced electronic modulation and improved solubility in polar aprotic solvents. It serves as a key building block for pharmaceutical intermediates and advanced synthetic scaffolds requiring precise functional group placement and stability under standard reaction conditions.

Application

2-Fluoro-4,5-dimethoxybenzaldehyde serves as a versatile building block in medicinal chemistry and materials synthesis, enabling efficient access to substituted benzimidazoles, heterocyclic scaffolds, and fluorinated aromatic systems. Its ortho-fluoro and adjacent dimethoxy groups provide enhanced reactivity in nucleophilic aromatic substitution and facilitate downstream functionalization via Pd-catalyzed coupling reactions. The compound exhibits good bench stability and simplifies purification due to its crystalline nature and distinct chromatographic profile.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   35.53
  • LogP   1.6554
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

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