Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Iodo-1H-imidazole

  • CAS No. 71759-89-2

  • Cat. No. CS-W002802
  • Purity≥95%
  • MDL No.MFCD01632213

*For research and further manufacturing use only, not for direct human use.

4-Iodo-1H-imidazole|CS-W002802

Structure of 71759-89-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 71759-89-2
  • Cat. No. CS-W002802
  • Purity ≥95%
  • MDL No. MFCD01632213
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₃IN₂
  • Molecular Weight 193.97
  • Synonym(s) 5-Iodo-1H-imidazole
  • SMILES IC1=CN=CN1

Description

4-Iodo-1H-imidazole is a bench-stable heterocyclic reagent featuring a reactive iodine atom at the 4-position, enabling efficient coupling in palladium-catalyzed cross-coupling reactions. The imidazole core provides enhanced solubility and stability compared to traditional aryl halides, facilitating incorporation into complex molecular architectures under mild conditions.

Application

4-Iodo-1H-imidazole serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient access to functionalized imidazoles. Its iodine substituent facilitates reliable Pd- or Ni-mediated coupling with aryl, heteroaryl, and alkenyl partners under standard conditions. The molecule exhibits excellent bench stability, ease of handling, and compatibility with common protecting groups, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • Imidazole Ondansetron Impurity|CS-0229601
      288-32-4
    • ~55%
    • In-stock
      4-Iodo-1H-imidazole|CS-W002802
      71759-89-2

    References

    • Bhilare, Sachin V.; Deorukhkar, Amol R.; Darvatkar, Nitin B.; Salunkhe, Manikrao M. Synthetic Communications, 2008 , vol. 38, # 17 p. 2881 - 2888
  • Route2
    • null|null
      1443425-57-7
    • ~59%
    • In-stock
      4-Iodo-1H-imidazole|CS-W002802
      71759-89-2

    References

    • Sandtorv, Alexander H.; Bjorsvik, Hans-Rene Advanced Synthesis and Catalysis, 2013 , vol. 355, # 2-3 p. 499 - 507
  • Route3

    References

    • Genentech, Inc. Patent: US2012/245144 A1, 2012 ; Location in patent: Page/Page column 118 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS05
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335-H318
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   28.68
  • LogP   1.0143
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Iodo-1H-imidazole sigma4-Iodo-1H-imidazole manufacturer4-Iodo-1H-imidazole price4-Iodo-1H-imidazole structure4-Iodo-1H-imidazole SDSbuy 4-Iodo-1H-imidazole4-Iodo-1H-imidazole supplier4-Iodo-1H-imidazole uses4-Iodo-1H-imidazole molecular weightprice of 4-Iodo-1H-imidazole4-Iodo-1H-imidazole chemical name formula of 4-Iodo-1H-imidazole
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label