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CS-W001157 4
Total: USD 88.00

5-Chloroisoindoline-1,3-dione

  • CAS No. 7147-90-2

  • Cat. No. CS-W022359
  • Purity≥98%
  • MDL No.MFCD08703319

*For research and further manufacturing use only, not for direct human use.

5-Chloroisoindoline-1,3-dione|CS-W022359

Structure of 7147-90-2

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General Information

  • CAS No. 7147-90-2
  • Cat. No. CS-W022359
  • Purity ≥98%
  • MDL No. MFCD08703319
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₄ClNO₂
  • Molecular Weight 181.58
  • Synonym(s) 5-chloro-1H-isoindole-1,3(2H)-dione
  • SMILES ClC1=CC2=C(C=C1)C(=O)NC2=O

Description

5-Chloroisoindoline-1,3-dione serves as a reactive electrophilic scaffold in synthetic organic chemistry, featuring a chlorinated isoindoline core that enables selective functionalization. This electron-deficient heterocycle integrates readily into complex molecular architectures under mild conditions.

Application

5-Chloroisoindoline-1,3-dione serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of substituted isoindolines and heterocyclic scaffolds. Its electrophilic chlorine substituent facilitates regioselective functionalization, while the electron-deficient dione framework enhances reactivity in nucleophilic substitution and cycloaddition processes. The compound exhibits excellent bench stability and compatibility with standard purification techniques, making it well-suited for use in medicinal chemistry campaigns and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.17
  • LogP   1.2236
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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