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Structure of 7147-14-0
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5-Nitro-1H-indole-3-carbonitrile features a fused bicyclic indole core bearing a nitro group at the 5-position and a nitrile at the 3-position. This electron-deficient scaffold enables direct incorporation into heterocyclic architectures, serving as a key building block for bioactive molecule synthesis under standard conditions.
5-Nitro-1H-indole-3-carbonitrile serves as a versatile building block for the synthesis of functionalized indole scaffolds. Its dual electron-withdrawing groups—nitro at C5 and cyano at C3—enhance electrophilicity for nucleophilic substitution and facilitate downstream transformations such as reduction, coupling reactions, and heterocycle elaboration. The compound exhibits good bench stability and is compatible with standard synthetic workflows, enabling efficient access to medicinally relevant indole derivatives in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: