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CS-W001157 4
Total: USD 88.00

2-(3-(((tert-Butoxycarbonyl)amino)methyl)phenyl)acetic acid

  • CAS No. 71420-95-6

  • Cat. No. CS-W006576
  • Purity≥97%
  • MDL No.MFCD06656429

*For research and further manufacturing use only, not for direct human use.

2-(3-(((tert-Butoxycarbonyl)amino)methyl)phenyl)acetic acid|CS-W006576

Structure of 71420-95-6

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General Information

  • CAS No. 71420-95-6
  • Cat. No. CS-W006576
  • Purity ≥97%
  • MDL No. MFCD06656429
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₉NO₄
  • Molecular Weight 265.30
  • Synonym(s) Boc-(3-aminomethylphenyl)acetic acid
  • SMILES O=C(O)CC1=CC=CC(CNC(OC(C)(C)C)=O)=C1

Description

This boronic acid derivative features a para-substituted aryl group flanked by a carboxylic acid and a tert-butoxycarbonyl-protected amine, enabling direct incorporation into peptide-coupling workflows. The Boc moiety provides stability during synthesis and can be selectively removed under mild acidic conditions, streamlining access to functionalized intermediates for medicinal chemistry applications.

Application

2-(3-(((tert-Butoxycarbonyl)amino)methyl)phenyl)acetic acid serves as a versatile building block for the synthesis of biologically relevant scaffolds, enabling efficient access to phenylalanine-derived motifs and heterocyclic systems. The protected amine group offers excellent stability and orthogonal deprotection compatibility, while the pendant carboxylic acid facilitates coupling reactions under standard conditions. Its well-defined reactivity profile supports reliable functionalization in medicinal chemistry campaigns and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   2.3384
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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