Lot numbers can be found on the outside label of a product:
4-Bromo-1-ethyl-1H-pyrazole
-
CAS No. 71229-85-1
- Cat. No. CS-W003481
- Purity≥97%
- MDL No.MFCD08235252
*For research and further manufacturing use only, not for direct human use.
Structure of 71229-85-1
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 71229-85-1
- Cat. No. CS-W003481
- Purity ≥97%
- MDL No. MFCD08235252
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₅H₇BrN₂
- Molecular Weight 175.03
- Synonym(s) None
- SMILES CCN1C=C(Br)C=N1
Description
4-Bromo-1-ethyl-1H-pyrazole is a bench-stable, moisture-tolerant heterocyclic building block featuring a bromine substituent at the 4-position and an ethyl group at the 1-position of the pyrazole core. This configuration enables direct functionalization in cross-coupling reactions, facilitating access to diverse pyrazole-based scaffolds for medicinal chemistry and materials science applications.
Application
4-Bromo-1-ethyl-1H-pyrazole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-established bromine reactivity. The ethyl group at the 1-position enhances solubility and stability, while the pyrazole core provides a robust heterocyclic scaffold with favorable pharmacophore properties. This compound facilitates efficient synthesis of substituted pyrazoles under standard coupling conditions, offering reliable functional group tolerance and straightforward purification—ideal for high-throughput screening and lead optimization workflows.
Synthesis
-
Route1
-
In-stock
2075-45-8 -
75-03-6 - ~84%
-
In-stock
71229-85-1
References
-
ORION CORPORATION; LINNANEN, Tero; WOHLFAHRT, Gerd; NANDURI, Srinivas; UJJINAMATADA, Ravi; RAJAGOPALAN, Srinivasan; MUKHERJEE, Subhendu Patent: WO2013/53983 A1, 2013 ; Location in patent: Page/Page column 36 ;
-
-
Route2
-
In-stock
2075-45-8
-
74-96-4
- ~77%
-
In-stock
71229-85-1
References
-
Ivachtchenko, Alexandre V.; Kravchenko, Dmitry V.; Zheludeva, Valentina I.; Pershin, Dmitry G. Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 6 p. 931 - 939
-
-
Route3
-
In-stock
2817-71-2 - ~%
-
In-stock
71229-85-1
References
-
Inorganic Chemistry, , vol. 51, # 17 p. 9385 - 9394
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 17.82
- LogP 1.6655
- H_Acceptors 2
- H_Donors 0
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 4-Bromo-1-ethyl-1H-pyrazole sigma4-Bromo-1-ethyl-1H-pyrazole manufacturer4-Bromo-1-ethyl-1H-pyrazole price4-Bromo-1-ethyl-1H-pyrazole structure4-Bromo-1-ethyl-1H-pyrazole SDSbuy 4-Bromo-1-ethyl-1H-pyrazole4-Bromo-1-ethyl-1H-pyrazole supplier4-Bromo-1-ethyl-1H-pyrazole uses4-Bromo-1-ethyl-1H-pyrazole molecular weightprice of 4-Bromo-1-ethyl-1H-pyrazole4-Bromo-1-ethyl-1H-pyrazole chemical name formula of 4-Bromo-1-ethyl-1H-pyrazole