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CS-W001157 4
Total: USD 88.00

(5-Amino-1,3-phenylene)dimethanol

  • CAS No. 71176-54-0

  • Cat. No. CS-W007237
  • Purity≥95%
  • MDL No.MFCD08690090

*For research and further manufacturing use only, not for direct human use.

(5-Amino-1,3-phenylene)dimethanol|CS-W007237

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General Information

  • CAS No. 71176-54-0
  • Cat. No. CS-W007237
  • Purity ≥95%
  • MDL No. MFCD08690090
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁NO₂
  • Molecular Weight 153.18
  • Synonym(s) 5-AMINO-1,3-DIHYDROXYMETHYLBENZENE
  • SMILES NC1=CC(CO)=CC(CO)=C1

Description

N-Acetyl-D-galactosamine is the initial O-linked sugar to many serine and threonine residues in protein glycosylation.

Application

(5-Amino-1,3-phenylene)dimethanol serves as a versatile bifunctional building block for the synthesis of heterocyclic scaffolds and functionalized aromatic systems. Its ortho-diamino and diol functionalities enable robust coupling reactions, including amide formation and cyclization pathways, with excellent bench stability and straightforward purification. Widely applicable in medicinal chemistry and materials science, it functions as a key intermediate in the construction of bioactive molecules and advanced polymers.

Synthesis

  • Route1

    References

    • IMMUNOGEN, INC.; LI, Wei; FISHKIN, Nathan, Elliott; ZHAO, Robert, Yongxin; MILLER, Michael, Louis; CHARI, Ravi, V., J. Patent: WO2010/91150 A1, 2010 ; Location in patent: Page/Page column 119-120 ;
  • Route2
    • Diethyl 5-aminoisophthalate|CS-0188319
      42122-73-6
    • ~92%
    • In-stock
      (5-Amino-1,3-phenylene)dimethanol|CS-W007237
      71176-54-0

    References

    • Bergbreiter, David E.; Osburn, Philip L.; Liu, Yun-Shan Journal of the American Chemical Society, 1999 , vol. 121, # 41 p. 9531 - 9538
  • Route3

    References

    • Yu, Kunquan; Sommer, William; Richardson, John M.; Weck, Marcus; Jones, Christopher W. Advanced Synthesis and Catalysis, 2005 , vol. 347, # 1 p. 161 - 171

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   66.48
  • LogP   0.2534
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   2

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