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CS-W001157 4
Total: USD 88.00

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one

  • CAS No. 710348-69-9

  • Cat. No. CS-0097961
  • Purity≥95%
  • MDL No.MFCD09260491
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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

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*For research and further manufacturing use only, not for direct human use.

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one|CS-0097961

Structure of 710348-69-9

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Description

This boronate-functionalized benzoimidazolone integrates readily into Suzuki-Miyaura coupling reactions under standard conditions. The tetramethylboronate moiety enhances stability and solubility, enabling efficient cross-coupling with aryl halides. This bench-stable reagent streamlines the synthesis of biaryl-linked heterocycles for medicinal chemistry applications.

Application

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The stable boronate ester group enables efficient C–C bond formation under mild conditions, while the benzo[d]imidazol-2-one scaffold provides a rigid, electron-deficient heterocyclic core with favorable solubility and bench stability. Functions reliably in diverse synthetic workflows, including late-stage functionalization and library synthesis.

General Information

  • CAS No. 710348-69-9
  • Cat. No. CS-0097961
  • Purity ≥95%
  • MDL No. MFCD09260491
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₇BN₂O₃
  • Molecular Weight None
  • Synonym(s) 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazol-2(3H)-one
  • SMILES O=C1NC2=CC=C(C=C2N1)B3OC(C)(C(C)(O3)C)C

Computational Chemistry Data

  • TPSA   67.11
  • LogP   1.1554
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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