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Structure of 70912-52-6
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This cyclic β-ketoester features a sterically hindered dimethyl substitution at the 2-position and a pyrrolidinylidene moiety at the 5-position, enhancing stability and modulating reactivity. The dioxane-dione core provides a rigid, electron-deficient scaffold ideal for Diels-Alder cycloadditions and heterocycle synthesis under mild conditions.
2,2-Dimethyl-5-(pyrrolidin-2-ylidene)-1,3-dioxane-4,6-dione serves as a stable, bench-ready Michael acceptor and key building block for heterocyclic synthesis. Its α,β-unsaturated dione framework enables efficient conjugate addition with nucleophiles, facilitating the construction of complex pyrrolidine and piperidine scaffolds. The molecule exhibits excellent functional group tolerance and simplifies purification due to its crystalline nature, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3259
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: